Which of the following is a primary use for digoxin immune Fab?

Explore the USMLE Step 3 Drug MOA Test. Use flashcards and multiple-choice questions, each with hints and explanations. Ace your exam with confidence!

Digoxin immune Fab is specifically used as an antidote for digoxin intoxication. Digoxin, a cardiac glycoside, is used in the treatment of heart failure and certain arrhythmias. However, in cases of overdose, symptoms can include nausea, vomiting, confusion, and potentially life-threatening arrhythmias.

The mechanism by which digoxin immune Fab works involves binding to digoxin molecules in the bloodstream. This binding forms a complex that is then excreted by the kidneys, effectively removing digoxin from circulation and mitigating its toxic effects. This makes digoxin immune Fab a crucial treatment option in emergency scenarios involving digoxin toxicity, rather than for routine management of heart failure or other conditions listed in the alternatives.

In contrast, while digoxin itself is utilized in managing heart failure, digoxin immune Fab is not used for this purpose, which underscores its unique role in the context of intoxication. The choices regarding hypertension management or antipsychotic therapy are unrelated to the pharmacological action of digoxin or its antidote.

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