Which of the following is a treatment for benign prostatic hyperplasia (BPH) by decreasing DHT?

The chosen answer is correct because Finasteride is a 5-alpha reductase inhibitor that specifically works by decreasing the levels of dihydrotestosterone (DHT) in the body. DHT is a potent androgen derived from testosterone and is known to contribute to the growth of prostate tissue, thereby worsening benign prostatic hyperplasia (BPH). By inhibiting the conversion of testosterone to DHT, Finasteride helps to reduce prostate size, relieve urinary symptoms associated with BPH, and improve urinary flow.

In contrast, the other options have different mechanisms of action and therapeutic uses. Acetaminophen is an analgesic and antipyretic agent that does not influence hormone levels or prostate growth. Valproic acid is primarily an anticonvulsant and mood-stabilizing drug without any role in managing BPH. Tamoxifen is a selective estrogen receptor modulator commonly used in the treatment of breast cancer; it does not target androgenic pathways relevant to the management of BPH. Thus, Finasteride's ability to directly influence DHT levels makes it the appropriate choice for treating this condition.