What role does ceruletide play in digestion?

Ceruletide, a synthetic analog of cholecystokinin (CCK), plays a significant role in digestion by stimulating gallbladder contraction. CCK is a hormone released by the small intestine in response to the presence of fats and amino acids, and it is primarily responsible for the digestion of these macronutrients.

When ceruletide is administered, it mimics the action of CCK by binding to CCK receptors in the pancreas and gallbladder. In the gallbladder, this binding prompts the contraction of the smooth muscle, facilitating the release of bile into the duodenum. Bile is crucial for the emulsification and digestion of fats, thereby enhancing nutrient absorption. By stimulating gallbladder contraction, ceruletide promotes the efficient preparation and digestion of dietary fats.

While stimulating gallbladder contraction is its key action, ceruletide also has other effects such as encouraging pancreatic enzyme secretion and enhancing intestinal motility. However, the primary role in this context regarding ceruletide’s specific action pertains to gallbladder contraction, making it the correct choice in this scenario.