What is one of the effects of statins on atherosclerosis besides lowering LDL cholesterol?

Statins are well known for their ability to lower LDL cholesterol levels, but they also have several other beneficial effects on cardiovascular health that contribute to the treatment of atherosclerosis. One significant effect is their anti-inflammatory properties.

Statins exert anti-inflammatory effects on endothelial cells, which are crucial for maintaining healthy vascular function. By reducing inflammation in the vascular endothelium, statins can improve endothelial function and reduce the progression of atherosclerotic plaques. This anti-inflammatory action helps to stabilize plaques and may prevent plaque rupture, ultimately reducing the risk of heart attacks and strokes.

In addition to their role in managing lipid profiles, this ability to modulate inflammatory processes is a key component of their overall protective effects on the cardiovascular system. It highlights that the benefits of statins extend beyond mere cholesterol management, impacting the underlying pathology of atherosclerosis.