How does levothyroxine function in hypothyroidism treatment?

Levothyroxine functions in the treatment of hypothyroidism primarily by increasing metabolism and regulating various bodily functions. This synthetic form of thyroxine (T4) acts as a replacement for the deficient thyroid hormone in individuals with hypothyroidism. Once administered, levothyroxine is converted to its active form, triiodothyronine (T3), in the body. T3 plays a crucial role in the regulation of metabolism, influencing processes such as protein synthesis, glucose metabolism, and thermogenesis. By restoring normal levels of thyroid hormone, levothyroxine helps to alleviate the symptoms associated with hypothyroidism, such as fatigue, weight gain, and cold intolerance, thereby enhancing overall physiological function and quality of life for the patient.